TY  - GEN
AU  - Nitzki,Frauke
AU  - Tolosa,Ezequiel J
AU  - Cuvelier,Nicole
AU  - Frommhold,Anke
AU  - Salinas-Riester,Gabriela
AU  - Johnsen,Steven A
AU  - Fernandez-Zapico,Martin E
AU  - Hahn,Heidi
TI  - Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy
SN  - 1949-2553
PY  - 2016///0301
KW  - Animals
KW  - Azacitidine
KW  - analogs & derivatives
KW  - CpG Islands
KW  - DNA Methylation
KW  - drug effects
KW  - Decitabine
KW  - Embryonic Development
KW  - genetics
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, Tumor Suppressor
KW  - Gestational Age
KW  - Heterozygote
KW  - Histones
KW  - metabolism
KW  - Kruppel-Like Transcription Factors
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Models, Genetic
KW  - Mutation
KW  - Neoplasm Proteins
KW  - biosynthesis
KW  - Patched Receptors
KW  - Patched-1 Receptor
KW  - Polymorphism, Single Nucleotide
KW  - Promoter Regions, Genetic
KW  - Protein Processing, Post-Translational
KW  - Receptors, Cell Surface
KW  - Rhabdomyosarcoma
KW  - Signal Transduction
KW  - Zinc Finger Protein GLI1
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.18632/oncotarget.3272
ER  -