Nitzki, Frauke

Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy. [electronic resource] - Oncotarget Apr 2015 - 9113-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.3272 doi


Animals
Azacitidine--analogs & derivatives
CpG Islands
DNA Methylation--drug effects
Decitabine
Embryonic Development--genetics
Gene Expression Regulation, Neoplastic--drug effects
Genes, Tumor Suppressor
Gestational Age
Heterozygote
Histones--metabolism
Kruppel-Like Transcription Factors--metabolism
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Knockout
Models, Genetic
Mutation
Neoplasm Proteins--biosynthesis
Patched Receptors
Patched-1 Receptor
Polymorphism, Single Nucleotide
Promoter Regions, Genetic--genetics
Protein Processing, Post-Translational
Receptors, Cell Surface--biosynthesis
Rhabdomyosarcoma--genetics
Signal Transduction
Zinc Finger Protein GLI1