TY - GEN AU - Wang,Xiaochun AU - Zhang,Jingyan AU - Liang,Jinping AU - Zhang,Ying AU - Teng,Xindong AU - Yuan,Xuefeng AU - Fan,Xionglin TI - Protection against Mycobacterium tuberculosis infection offered by a new multistage subunit vaccine correlates with increased number of IFN-γ+ IL-2+ CD4+ and IFN-γ+ CD8+ T cells SN - 1932-6203 PY - 2016///0309 KW - Adjuvants, Immunologic KW - pharmacology KW - Adolescent KW - Adult KW - Aged KW - Animals KW - Antibodies, Bacterial KW - immunology KW - Antigens, Bacterial KW - blood KW - Bacterial Load KW - CD4-Positive T-Lymphocytes KW - CD8-Positive T-Lymphocytes KW - Female KW - Humans KW - Immunization KW - Interferon-gamma KW - metabolism KW - Interleukin-2 KW - Lung KW - microbiology KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Mycobacterium tuberculosis KW - Polyproteins KW - Th1 Cells KW - Tuberculosis KW - prevention & control KW - Tuberculosis Vaccines KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0122560 ER -