TY  - GEN
AU  - Smith,Gaynor A
AU  - Rocha,Emily M
AU  - Rooney,Thomas
AU  - Barneoud,Pascal
AU  - McLean,Jesse R
AU  - Beagan,Jonathan
AU  - Osborn,Teresia
AU  - Coimbra,Madeleine
AU  - Luo,Yongyi
AU  - Hallett,Penelope J
AU  - Isacson,Ole
TI  - A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C)
SN  - 1932-6203
PY  - 2016///0218
KW  - Animals
KW  - Disease Models, Animal
KW  - Dopamine
KW  - biosynthesis
KW  - Dopaminergic Neurons
KW  - metabolism
KW  - Gene Expression
KW  - Imidazoles
KW  - administration & dosage
KW  - Inflammation
KW  - chemically induced
KW  - Male
KW  - Microglia
KW  - Nerve Degeneration
KW  - drug therapy
KW  - Neuroprotection
KW  - drug effects
KW  - Nuclear Receptor Subfamily 4, Group A, Member 2
KW  - agonists
KW  - Oxidopamine
KW  - toxicity
KW  - Parkinson Disease, Secondary
KW  - Pars Compacta
KW  - Poly I-C
KW  - Pyridines
KW  - RNA, Double-Stranded
KW  - Rats
KW  - Toll-Like Receptor 3
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0121072
ER  -