TY  - GEN
AU  - Hollevoet,Kevin
AU  - Mason-Osann,Emily
AU  - Müller,Fabian
AU  - Pastan,Ira
TI  - Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line
SN  - 1932-6203
PY  - 2016///0216
KW  - ADP Ribose Transferases
KW  - immunology
KW  - Apoptosis
KW  - drug effects
KW  - Bacterial Toxins
KW  - Base Sequence
KW  - Blotting, Western
KW  - Cell Count
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - DNA Methylation
KW  - Drug Resistance, Neoplasm
KW  - physiology
KW  - Exotoxins
KW  - Flow Cytometry
KW  - GPI-Linked Proteins
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Immunoglobulin Variable Region
KW  - Immunotoxins
KW  - Mesothelin
KW  - Molecular Sequence Data
KW  - Pancreatic Neoplasms
KW  - metabolism
KW  - Real-Time Polymerase Chain Reaction
KW  - Recombinant Proteins
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sequence Analysis, RNA
KW  - Virulence Factors
KW  - Pseudomonas aeruginosa Exotoxin A
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0122462
ER  -