TY - GEN AU - Yang,Li AU - Islam,Mohammad R AU - Karamyan,Vardan T AU - Abbruscato,Thomas J TI - In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment SN - 1872-6240 PY - 2016///0120 KW - 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer KW - chemistry KW - Analgesics, Opioid KW - Brain Edema KW - drug therapy KW - Brain Infarction KW - Brain Ischemia KW - Cells, Cultured KW - Enkephalin, Ala(2)-MePhe(4)-Gly(5)- KW - Enkephalin, D-Penicillamine (2,5)- KW - Enkephalins KW - Glutamic Acid KW - toxicity KW - Ischemia KW - Motor Activity KW - drug effects KW - Neurons KW - Neuroprotective Agents KW - Receptors, Opioid, delta KW - agonists KW - Receptors, Opioid, kappa KW - Receptors, Opioid, mu KW - Reperfusion Injury KW - Severity of Illness Index KW - Stroke N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.brainres.2015.03.022 ER -