TY - GEN AU - Mefford,Megan E AU - Kunstman,Kevin AU - Wolinsky,Steven M AU - Gabuzda,Dana TI - Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5 SN - 1096-0341 PY - 2015///0803 KW - Amino Acid Sequence KW - Brain KW - metabolism KW - Computational Biology KW - HIV Envelope Protein gp120 KW - chemistry KW - HIV Infections KW - genetics KW - HIV-1 KW - Humans KW - Macrophages KW - Molecular Sequence Data KW - Polymorphism, Single Nucleotide KW - Protein Binding KW - Protein Structure, Secondary KW - Receptors, CCR5 KW - Sequence Alignment KW - Viral Tropism N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.virol.2015.01.032 ER -