Foo, Jhi Biau <br/><br/>
Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway.  [electronic resource] 

 -  Journal of ethnopharmacology  May 2015 
 - 270-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1872-7573 
<br/><br/><label>Standard No.: </label>10.1016/j.jep.2015.03.039  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Cell Line, Tumor<br/>Cyclin-Dependent Kinase Inhibitor p21--metabolism<br/>Dilleniaceae--chemistry<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>MCF-7 Cells<br/>Mitochondria--drug effects<br/>Pentacyclic Triterpenes<br/>Plant Extracts--chemistry<br/>Plant Roots--chemistry<br/>Protein Processing, Post-Translational--drug effects<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>RNA, Messenger--metabolism<br/>Resting Phase, Cell Cycle--drug effects<br/>Signal Transduction--drug effects<br/>Triterpenes--pharmacology<br/>Tumor Suppressor Protein p53--metabolism<br/>bcl-2-Associated X Protein--drug effects<br/>Betulinic Acid