GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS. [electronic resource]
- Atherosclerosis May 2015
- 163-73 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
1879-1484
10.1016/j.atherosclerosis.2015.03.013 doi
Cells, Cultured Dose-Response Relationship, Drug Endothelial Cells--drug effects Humans Hydrolysis Inflammation--enzymology Inflammation Mediators--metabolism Interleukin-6--genetics Lipopolysaccharides--pharmacology Microvessels--drug effects Mitogen-Activated Protein Kinases--metabolism NF-kappa B--genetics Palmitic Acid--pharmacology RNA Interference Receptors, G-Protein-Coupled--genetics Signal Transduction--drug effects Sphingomyelin Phosphodiesterase--genetics Sphingomyelins--metabolism Time Factors Transfection Up-Regulation