TY - GEN AU - Buchanan,Andrew AU - Newton,Philip AU - Pehrsson,Susanne AU - Inghardt,Tord AU - Antonsson,Thomas AU - Svensson,Peder AU - Sjögren,Tove AU - Öster,Linda AU - Janefeldt,Annika AU - Sandinge,Ann-Sofie AU - Keyes,Feenagh AU - Austin,Mark AU - Spooner,Jennifer AU - Gennemark,Peter AU - Penney,Mark AU - Howells,Garnet AU - Vaughan,Tristan AU - Nylander,Sven TI - Structural and functional characterization of a specific antidote for ticagrelor SN - 1528-0020 PY - 2015///0825 KW - Adenosine KW - analogs & derivatives KW - Animals KW - Antibodies KW - isolation & purification KW - Antibodies, Neutralizing KW - chemistry KW - Antibody Specificity KW - Antidotes KW - Broadly Neutralizing Antibodies KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Crystallography, X-Ray KW - Hemorrhage KW - prevention & control KW - Humans KW - Immunoglobulin Fab Fragments KW - pharmacology KW - Mice KW - Models, Molecular KW - Platelet Aggregation KW - drug effects KW - Protein Engineering KW - Ticagrelor N1 - Publication Type: Journal Article UR - https://doi.org/10.1182/blood-2015-01-622928 ER -