TY  - GEN
AU  - Zhao,Yun-peng
AU  - Tian,Qing-yun
AU  - Liu,Ben
AU  - Cuellar,Jason
AU  - Richbourgh,Brendon
AU  - Jia,Tang-hong
AU  - Liu,Chuan-ju
TI  - Progranulin knockout accelerates intervertebral disc degeneration in aging mice
SN  - 2045-2322
PY  - 2016///0224
KW  - Age Factors
KW  - Animals
KW  - Bone Resorption
KW  - genetics
KW  - Cartilage
KW  - metabolism
KW  - Disease Models, Animal
KW  - Disease Progression
KW  - Gene Expression
KW  - Genetic Association Studies
KW  - Granulins
KW  - Humans
KW  - Immunohistochemistry
KW  - Intercellular Signaling Peptides and Proteins
KW  - deficiency
KW  - Intervertebral Disc
KW  - Intervertebral Disc Degeneration
KW  - diagnosis
KW  - Mice
KW  - Mice, Knockout
KW  - NF-kappa B
KW  - Osteoclasts
KW  - Osteogenesis
KW  - Progranulins
KW  - Signal Transduction
KW  - Spine
KW  - X-Ray Microtomography
KW  - beta Catenin
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/srep09102
ER  -