TY - GEN AU - Nishikawa,Taichiro AU - Bell,Aaron AU - Brooks,Jenna M AU - Setoyama,Kentaro AU - Melis,Marta AU - Han,Bing AU - Fukumitsu,Ken AU - Handa,Kan AU - Tian,Jianmin AU - Kaestner,Klaus H AU - Vodovotz,Yoram AU - Locker,Joseph AU - Soto-Gutierrez,Alejandro AU - Fox,Ira J TI - Resetting the transcription factor network reverses terminal chronic hepatic failure SN - 1558-8238 PY - 2015///0702 KW - Animals KW - CCAAT-Enhancer-Binding Protein-alpha KW - biosynthesis KW - Carbon Tetrachloride Poisoning KW - genetics KW - Cell Dedifferentiation KW - Cells, Cultured KW - Dependovirus KW - Disease Progression KW - Down-Regulation KW - Gene Expression Profiling KW - Gene Expression Regulation KW - Gene Regulatory Networks KW - Genetic Therapy KW - Genetic Vectors KW - therapeutic use KW - Hepatocyte Nuclear Factor 1-alpha KW - Hepatocyte Nuclear Factor 3-beta KW - Hepatocyte Nuclear Factor 4 KW - Hepatocytes KW - metabolism KW - Liver Cirrhosis, Experimental KW - complications KW - Liver Failure KW - etiology KW - Male KW - PPAR alpha KW - Rats KW - Rats, Inbred Lew KW - Recombinant Fusion Proteins KW - Transcription Factors KW - physiology KW - Transcriptome KW - Transduction, Genetic N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1172/JCI73137 ER -