TY - GEN AU - Wang,Peng AU - Zhao,Wei AU - Zhao,Kai AU - Zhang,Lei AU - Gao,Chengjiang TI - TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3 SN - 1553-7374 PY - 2015///0731 KW - Animals KW - Blotting, Western KW - Cell Nucleus KW - metabolism KW - Enzyme-Linked Immunosorbent Assay KW - Fluorescent Antibody Technique KW - Interferon Regulatory Factor-3 KW - Interferon-beta KW - biosynthesis KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Reverse Transcriptase Polymerase Chain Reaction KW - Rhabdoviridae Infections KW - immunology KW - Transfection KW - Tripartite Motif Proteins KW - Ubiquitin-Protein Ligases KW - Ubiquitination KW - Vesiculovirus N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.ppat.1004726 ER -