Rizzo, Joseph M

Application of a high-throughput relative chemical stability assay to screen therapeutic protein formulations by assessment of conformational stability and correlation to aggregation propensity. [electronic resource] - Journal of pharmaceutical sciences May 2015 - 1632-40 p. digital

Publication Type: Journal Article

1520-6017

10.1002/jps.24408 doi


Antibodies, Monoclonal--chemistry
Chemistry, Pharmaceutical
Circular Dichroism--methods
Drug Evaluation, Preclinical--methods
High-Throughput Screening Assays--methods
Protein Aggregates
Protein Conformation
Recombinant Proteins--chemistry
Spectrometry, Fluorescence--methods