TY - GEN AU - Ueno,Manabu AU - Maeno,Toshitaka AU - Nishimura,Satoshi AU - Ogata,Fusa AU - Masubuchi,Hiroaki AU - Hara,Kenichiro AU - Yamaguchi,Kouichi AU - Aoki,Fumiaki AU - Suga,Tatsuo AU - Nagai,Ryozo AU - Kurabayashi,Masahiko TI - Alendronate inhalation ameliorates elastase-induced pulmonary emphysema in mice by induction of apoptosis of alveolar macrophages SN - 2041-1723 PY - 2016///0209 KW - Administration, Inhalation KW - Aerosols KW - Alendronate KW - pharmacology KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - Antigens, Differentiation KW - genetics KW - Apoptosis KW - drug effects KW - Bone Density Conservation Agents KW - Bronchoalveolar Lavage Fluid KW - chemistry KW - CD11b Antigen KW - CD11c Antigen KW - Caspase 3 KW - Cell Movement KW - Contrast Media KW - metabolism KW - Drug Repositioning KW - Gene Expression KW - Lung KW - Macrophages, Alveolar KW - Male KW - Mevalonic Acid KW - immunology KW - Mice KW - Mice, Inbred C57BL KW - NF-kappa B KW - Pancreatic Elastase KW - Phagocytosis KW - Pulmonary Emphysema KW - chemically induced KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncomms7332 ER -