Yang, Chenyi

CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity. [electronic resource] - Cancer research May 2015 - 1838-45 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1538-7445

10.1158/0008-5472.CAN-14-2486 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Cell Line
Cyclin-Dependent Kinase 4--antagonists & inhibitors
Cyclin-Dependent Kinase 6--antagonists & inhibitors
Cytarabine--pharmacology
DNA Damage--drug effects
DNA Replication--drug effects
HEK293 Cells
HL-60 Cells
Humans
Leukemia, Myeloid, Acute--drug therapy
Mice, Inbred NOD
Mice, SCID
Phosphorylation--drug effects
Piperazines--pharmacology
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-pim-1--genetics
Pyridines--pharmacology
S Phase--drug effects
Transcription, Genetic--drug effects
Tumor Cells, Cultured
Xenograft Model Antitumor Assays