TY - GEN AU - Tian,Zhenhua AU - Sun,Peng AU - Yan,Yan AU - Wu,Zhuhua AU - Zheng,Qingfei AU - Zhou,Shuaixiang AU - Zhang,Hua AU - Yu,Futao AU - Jia,Xinying AU - Chen,Dandan AU - Mándi,Attila AU - Kurtán,Tibor AU - Liu,Wen TI - An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins SN - 1552-4469 PY - 2015///0602 KW - Alkenes KW - chemistry KW - Biological Products KW - Catalysis KW - Chemistry KW - methods KW - Cyclization KW - Cyclohexenes KW - DNA, Bacterial KW - Intramolecular Lyases KW - chemical synthesis KW - Macrolides KW - Models, Chemical KW - Molecular Structure KW - Mutation KW - Plasmids KW - metabolism KW - Pyrrolidinones KW - Recombinant Proteins KW - Stereoisomerism KW - Streptomyces N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nchembio.1769 ER -