Tian, Zhenhua

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins. [electronic resource] - Nature chemical biology Apr 2015 - 259-65 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4469

10.1038/nchembio.1769 doi


Alkenes--chemistry
Biological Products--chemistry
Catalysis
Chemistry--methods
Cyclization
Cyclohexenes--chemistry
DNA, Bacterial--chemistry
Intramolecular Lyases--chemical synthesis
Macrolides--chemical synthesis
Models, Chemical
Molecular Structure
Mutation
Plasmids--metabolism
Pyrrolidinones--chemical synthesis
Recombinant Proteins--chemistry
Stereoisomerism
Streptomyces--metabolism