Pan, Wei-Kang <br/><br/>
Propranolol induces regression of hemangioma cells via the down-regulation of the PI3K/Akt/eNOS/VEGF pathway.  [electronic resource] 

 -  Pediatric blood & cancer  Aug 2015 
 - 1414-20 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1545-5017 
<br/><br/><label>Standard No.: </label>10.1002/pbc.25453  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenergic beta-Antagonists--therapeutic use<br/>Angiogenesis Inhibitors--therapeutic use<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Proliferation--drug effects<br/>Cells, Cultured<br/>Chromones--pharmacology<br/>Cinnamates--pharmacology<br/>Cyclin A2--biosynthesis<br/>Cyclin D2--biosynthesis<br/>Cyclin-Dependent Kinase Inhibitor p21--biosynthesis<br/>Endothelial Cells--metabolism<br/>Hemangioma--drug therapy<br/>Humans<br/>Infant<br/>Infant, Newborn<br/>Morpholines--pharmacology<br/>NG-Nitroarginine Methyl Ester--pharmacology<br/>Neoplasm Invasiveness--pathology<br/>Neovascularization, Pathologic--drug therapy<br/>Nitric Oxide--biosynthesis<br/>Nitric Oxide Synthase Type III--antagonists & inhibitors<br/>Norepinephrine--pharmacology<br/>Pericytes--metabolism<br/>Phosphatidylinositol 3-Kinases--biosynthesis<br/>Phosphoinositide-3 Kinase Inhibitors<br/>Phosphorylation<br/>Proliferating Cell Nuclear Antigen--biosynthesis<br/>Propranolol--therapeutic use<br/>Proto-Oncogene Proteins c-akt--biosynthesis<br/>Vascular Endothelial Growth Factor A--antagonists & inhibitors<br/>Vascular Endothelial Growth Factor Receptor-1--pharmacology<br/>Vascular Endothelial Growth Factor Receptor-2--antagonists & inhibitors