PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects. [electronic resource]
- Oncotarget Feb 2015
- 4299-314 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1949-2553
10.18632/oncotarget.3012 doi
Adult Aged Aged, 80 and over Animals Antibiotics, Antineoplastic--pharmacology Biomarkers, Tumor--analysis Blotting, Western Breast Neoplasms--drug therapy Doxorubicin--pharmacology Drug Resistance, Neoplasm--physiology Enzyme Activation--physiology Female Humans Immunohistochemistry Kaplan-Meier Estimate Mice Mice, Inbred BALB C Middle Aged Prognosis Protein Phosphatase 2--metabolism Real-Time Polymerase Chain Reaction Treatment Outcome