TY - GEN AU - Yi,Yong Weon AU - Kang,Hyo Jin AU - Bae,Edward Jeong AU - Oh,Seunghoon AU - Seong,Yeon-Sun AU - Bae,Insoo TI - β-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells SN - 2092-6413 PY - 2015///0916 KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - drug effects KW - Cyclin E KW - genetics KW - Dose-Response Relationship, Drug KW - Female KW - Furans KW - pharmacology KW - Gene Knockdown Techniques KW - Humans KW - Mechanistic Target of Rapamycin Complex 2 KW - Models, Biological KW - Multiprotein Complexes KW - antagonists & inhibitors KW - Phosphoinositide-3 Kinase Inhibitors KW - Phosphorylation KW - Protein Kinase Inhibitors KW - Proteolysis KW - Proto-Oncogene Proteins c-myc KW - Pyridines KW - Pyrimidines KW - TOR Serine-Threonine Kinases KW - Triple Negative Breast Neoplasms KW - beta-Transducin Repeat-Containing Proteins N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/emm.2014.127 ER -