TY - GEN AU - Wu,Qing-Qing AU - Xu,Man AU - Yuan,Yuan AU - Li,Fang-Fang AU - Yang,Zheng AU - Liu,Yuan AU - Zhou,Meng-Qiao AU - Bian,Zhou-Yan AU - Deng,Wei AU - Gao,Lu AU - Li,Hongliang AU - Tang,Qi-Zhu TI - Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway SN - 1522-1539 PY - 2015///0709 KW - Animals KW - Apoptosis KW - Cathepsin B KW - antagonists & inhibitors KW - Disease Models, Animal KW - Female KW - Fibrosis KW - HEK293 Cells KW - Humans KW - Hypertrophy, Left Ventricular KW - enzymology KW - JNK Mitogen-Activated Protein Kinases KW - MAP Kinase Kinase Kinase 5 KW - metabolism KW - Male KW - Mice, Knockout KW - Myocytes, Cardiac KW - drug effects KW - Protein Kinase Inhibitors KW - pharmacology KW - RNA Interference KW - Signal Transduction KW - Transfection KW - Tumor Necrosis Factor-alpha KW - Ventricular Function, Left KW - Ventricular Remodeling N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpheart.00601.2014 ER -