Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model. [electronic resource]
- Psychopharmacology Jul 2015
- 2463-79 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1432-2072
10.1007/s00213-015-3884-3 doi
Animals Anticonvulsants--pharmacokinetics Avoidance Learning--drug effects Benzhydryl Compounds--pharmacology Brain--drug effects Carbamazepine--pharmacokinetics Central Nervous System Stimulants--pharmacology Dose-Response Relationship, Drug Drug Interactions Drug Synergism Electroshock Hand Strength Male Mice Modafinil Phenobarbital--pharmacokinetics Phenytoin--pharmacokinetics Psychomotor Performance--drug effects Seizures--prevention & control Sulfones--pharmacology Valproic Acid--pharmacokinetics