TY  - GEN
AU  - Coll,Rebecca C
AU  - Robertson,Avril A B
AU  - Chae,Jae Jin
AU  - Higgins,Sarah C
AU  - Muñoz-Planillo,Raúl
AU  - Inserra,Marco C
AU  - Vetter,Irina
AU  - Dungan,Lara S
AU  - Monks,Brian G
AU  - Stutz,Andrea
AU  - Croker,Daniel E
AU  - Butler,Mark S
AU  - Haneklaus,Moritz
AU  - Sutton,Caroline E
AU  - Núñez,Gabriel
AU  - Latz,Eicke
AU  - Kastner,Daniel L
AU  - Mills,Kingston H G
AU  - Masters,Seth L
AU  - Schroder,Kate
AU  - Cooper,Matthew A
AU  - O'Neill,Luke A J
TI  - A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
SN  - 1546-170X
PY  - 2015///0501
KW  - Animals
KW  - Carrier Proteins
KW  - antagonists & inhibitors
KW  - Cryopyrin-Associated Periodic Syndromes
KW  - drug therapy
KW  - Disease Models, Animal
KW  - Encephalomyelitis, Autoimmune, Experimental
KW  - Furans
KW  - Heterocyclic Compounds, 4 or More Rings
KW  - pharmacology
KW  - Humans
KW  - Indenes
KW  - Inflammasomes
KW  - Inflammation
KW  - Interleukin-1beta
KW  - drug effects
KW  - Mice
KW  - Multiple Sclerosis
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
KW  - Sulfonamides
KW  - Sulfones
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/nm.3806
ER  -