TY - GEN AU - Ahronian,Leanne G AU - Sennott,Erin M AU - Van Allen,Eliezer M AU - Wagle,Nikhil AU - Kwak,Eunice L AU - Faris,Jason E AU - Godfrey,Jason T AU - Nishimura,Koki AU - Lynch,Kerry D AU - Mermel,Craig H AU - Lockerman,Elizabeth L AU - Kalsy,Anuj AU - Gurski,Joseph M AU - Bahl,Samira AU - Anderka,Kristin AU - Green,Lisa M AU - Lennon,Niall J AU - Huynh,Tiffany G AU - Mino-Kenudson,Mari AU - Getz,Gad AU - Dias-Santagata,Dora AU - Iafrate,A John AU - Engelman,Jeffrey A AU - Garraway,Levi A AU - Corcoran,Ryan B TI - Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations SN - 2159-8290 PY - 2016///0112 KW - Antineoplastic Agents KW - pharmacology KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - diagnosis KW - Drug Resistance, Neoplasm KW - drug effects KW - ErbB Receptors KW - antagonists & inhibitors KW - Gene Amplification KW - Humans KW - MAP Kinase Kinase 1 KW - genetics KW - MAP Kinase Signaling System KW - Mitogen-Activated Protein Kinase Kinases KW - Mutation KW - Oncogene Protein p21(ras) KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins B-raf KW - Transcriptional Activation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1158/2159-8290.CD-14-1518 ER -