Ahronian, Leanne G <br/><br/>
Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations.  [electronic resource] 

 -  Cancer discovery  Apr 2015 
 - 358-67 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>2159-8290 
<br/><br/><label>Standard No.: </label>10.1158/2159-8290.CD-14-1518  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--pharmacology<br/>Cell Line, Tumor<br/>Colorectal Neoplasms--diagnosis<br/>Drug Resistance, Neoplasm--drug effects<br/>ErbB Receptors--antagonists & inhibitors<br/>Gene Amplification<br/>Humans<br/>MAP Kinase Kinase 1--genetics<br/>MAP Kinase Signaling System--drug effects<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Mutation<br/>Oncogene Protein p21(ras)--genetics<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Transcriptional Activation