Transformation to a squamous cell carcinoma phenotype of an EGFR-mutated NSCLC patient after treatment with an EGFR-tyrosine kinase inhibitor. [electronic resource]
- Journal of clinical pathology Apr 2015
- 320-1 p. digital
Publication Type: Case Reports; Letter
1472-4146
10.1136/jclinpath-2015-202866 doi
Antineoplastic Agents--therapeutic use Biomarkers, Tumor--genetics Biopsy Carcinoma, Non-Small-Cell Lung--drug therapy Carcinoma, Squamous Cell--enzymology DNA Mutational Analysis Disease Progression Drug Resistance, Neoplasm ErbB Receptors--antagonists & inhibitors Erlotinib Hydrochloride Fatal Outcome Female Genetic Predisposition to Disease Humans Lung Neoplasms--drug therapy Middle Aged Molecular Targeted Therapy Mutation Phenotype Protein Kinase Inhibitors--therapeutic use Quinazolines--therapeutic use Time Factors Treatment Outcome