TY - GEN AU - Zhao,Baoyu AU - Gandhi,Sonu AU - Yuan,Cai AU - Luo,Zhipu AU - Li,Rui AU - Gårdsvoll,Henrik AU - de Lorenzi,Valentina AU - Sidenius,Nicolai AU - Huang,Mingdong AU - Ploug,Michael TI - Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation SN - 1089-8638 PY - 2015///0519 KW - Amino Acid Sequence KW - Antibodies, Monoclonal KW - immunology KW - Binding Sites KW - Cell Adhesion KW - Crystallography, X-Ray KW - Epitope Mapping KW - Humans KW - Kinetics KW - Ligands KW - Models, Molecular KW - Molecular Sequence Data KW - Protein Conformation KW - Protein Structure, Tertiary KW - Pseudopodia KW - metabolism KW - Receptors, Urokinase Plasminogen Activator KW - chemistry KW - Sequence Homology, Amino Acid KW - Signal Transduction KW - Somatomedins KW - Surface Plasmon Resonance KW - Urokinase-Type Plasminogen Activator KW - Vitronectin N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1016/j.jmb.2015.01.022 ER -