TY - GEN AU - Jiang,Feng AU - Chen,Lei AU - Yang,Ying-Cheng AU - Wang,Xian-Ming AU - Wang,Ruo-Yu AU - Li,Liang AU - Wen,Wen AU - Chang,Yan-Xin AU - Chen,Cai-Yang AU - Tang,Jing AU - Liu,Gao-Mi-Yang AU - Huang,Wen-Tao AU - Xu,Lin AU - Wang,Hong-Yang TI - CYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling SN - 1538-7445 PY - 2016///0123 KW - Animals KW - Carcinoma, Hepatocellular KW - enzymology KW - Cell Movement KW - Cytochrome P-450 CYP3A KW - physiology KW - Down-Regulation KW - Gene Expression Regulation, Neoplastic KW - Genes, Tumor Suppressor KW - Humans KW - Kaplan-Meier Estimate KW - Liver Neoplasms KW - Lung Neoplasms KW - Mechanistic Target of Rapamycin Complex 2 KW - Mice, Nude KW - Multiprotein Complexes KW - metabolism KW - Neoplasm Invasiveness KW - Neoplasm Transplantation KW - Prognosis KW - Proportional Hazards Models KW - Protein Processing, Post-Translational KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - TOR Serine-Threonine Kinases KW - Tissue Inhibitor of Metalloproteinase-1 KW - genetics KW - Tissue Inhibitor of Metalloproteinase-2 KW - Transcriptional Activation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-14-1589 ER -