Rao, Krishnamurthy Narasimha

AFN-1252 is a potent inhibitor of enoyl-ACP reductase from Burkholderia pseudomallei--Crystal structure, mode of action, and biological activity. [electronic resource] - Protein science : a publication of the Protein Society May 2015 - 832-40 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1469-896X

10.1002/pro.2655 doi


Anti-Bacterial Agents--chemistry
Benzofurans--chemistry
Burkholderia pseudomallei--drug effects
Crystallography, X-Ray
Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)--antagonists & inhibitors
Humans
Kinetics
Melioidosis--drug therapy
Pyrones--chemistry
Staphylococcal Infections--drug therapy