Zaveri, Nurulain T <br/><br/>
Discovery of the first small-molecule opioid pan antagonist with nanomolar affinity at mu, delta, kappa, and nociceptin opioid receptors.  [electronic resource] 

 -  ACS chemical neuroscience  Apr 2015 
 - 646-57 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural 
<br/><br/><label>ISSN: </label>1948-7193 
<br/><br/><label>Standard No.: </label>10.1021/cn500367b  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analgesics, Opioid--chemistry<br/>Animals<br/>CHO Cells<br/>Cell Membrane--drug effects<br/>Cricetulus<br/>Dose-Response Relationship, Drug<br/>Guanosine 5'-O-(3-Thiotriphosphate)--chemistry<br/>Humans<br/>Models, Chemical<br/>Molecular Structure<br/>Narcotic Antagonists--chemical synthesis<br/>Piperidines--chemical synthesis<br/>Protein Binding<br/>Receptors, Opioid--metabolism<br/>Receptors, Opioid, delta--antagonists & inhibitors<br/>Receptors, Opioid, kappa--antagonists & inhibitors<br/>Receptors, Opioid, mu--antagonists & inhibitors<br/>Sulfur Radioisotopes--chemistry<br/>Tetrahydroisoquinolines--chemistry<br/>Transfection<br/>Nociceptin Receptor