Zhuo, Xiaoliang

Identification of glutathione conjugates of acetylene-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Apr 2015 - 578-89 p. digital

Publication Type: Journal Article

1521-009X

10.1124/dmd.114.061879 doi


Alkynes--chemistry
Allosteric Regulation--drug effects
Animals
Cytosol--metabolism
Glutathione--metabolism
Humans
Liver--cytology
Metabolic Detoxication, Phase II
Microsomes, Liver--metabolism
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Rats
Receptor, Metabotropic Glutamate 5--metabolism
Structure-Activity Relationship