Huleatt, Paul B

Novel arylalkenylpropargylamines as neuroprotective, potent, and selective monoamine oxidase B inhibitors for the treatment of Parkinson's disease. [electronic resource] - Journal of medicinal chemistry Feb 2015 - 1400-19 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm501722s doi


Animals
Cell Survival--drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Humans
Mice
Molecular Structure
Monoamine Oxidase--metabolism
Monoamine Oxidase Inhibitors--chemical synthesis
Neuroprotective Agents--chemical synthesis
PC12 Cells
Pargyline--analogs & derivatives
Parkinson Disease--drug therapy
Propylamines--chemical synthesis
Rats
Structure-Activity Relationship