TY - GEN AU - Manzano-Moreno,Francisco Javier AU - Ramos-Torrecillas,Javier AU - De Luna-Bertos,Elvira AU - Ruiz,Concepción AU - García-Martínez,Olga TI - High doses of bisphosphonates reduce osteoblast-like cell proliferation by arresting the cell cycle and inducing apoptosis SN - 1878-4119 PY - 2016///0802 KW - Alendronate KW - administration & dosage KW - Apoptosis KW - drug effects KW - Bisphosphonate-Associated Osteonecrosis of the Jaw KW - pathology KW - Bone Density Conservation Agents KW - Cell Cycle KW - Cell Death KW - Cell Line, Tumor KW - Cell Proliferation KW - Clodronic Acid KW - Coloring Agents KW - Diphosphonates KW - Dose-Response Relationship, Drug KW - Flow Cytometry KW - methods KW - G1 Phase KW - Humans KW - Ibandronic Acid KW - Necrosis KW - Osteoblasts KW - Pamidronate KW - Resting Phase, Cell Cycle KW - Spectrophotometry KW - Tetrazolium Salts KW - Thiazoles KW - Time Factors N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.jcms.2014.12.008 ER -