TY  - GEN
AU  - Sagawa,Morihiko
AU  - Tabayashi,Takayuki
AU  - Kimura,Yuta
AU  - Tomikawa,Tatsuki
AU  - Nemoto-Anan,Tomoe
AU  - Watanabe,Reiko
AU  - Tokuhira,Michihide
AU  - Ri,Masaki
AU  - Hashimoto,Yuichi
AU  - Iida,Shinsuke
AU  - Kizaki,Masahiro
TI  - TM-233, a novel analog of 1'-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities
SN  - 1349-7006
PY  - 2015///0804
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Benzyl Alcohols
KW  - chemistry
KW  - Boronic Acids
KW  - Bortezomib
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Drug Resistance, Neoplasm
KW  - G1 Phase Cell Cycle Checkpoints
KW  - Humans
KW  - Janus Kinase 2
KW  - antagonists & inhibitors
KW  - Multiple Myeloma
KW  - enzymology
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - biosynthesis
KW  - NF-kappa B
KW  - Proteasome Endopeptidase Complex
KW  - metabolism
KW  - Proteasome Inhibitors
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Pyrazines
KW  - Quantitative Structure-Activity Relationship
KW  - STAT3 Transcription Factor
KW  - bcl-X Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/cas.12616
ER  -