Li, H-Y <br/><br/>
Celastrol induces apoptosis and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells: an in vitro and in vivo study.  [electronic resource] 

 -  Cell death & disease  Jan 2015 
 - e1604 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-4889 
<br/><br/><label>Standard No.: </label>10.1038/cddis.2014.543  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Autophagy--drug effects<br/>Caspases--metabolism<br/>Cell Cycle Checkpoints--drug effects<br/>Cell Cycle Proteins--metabolism<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Enzyme Activation--drug effects<br/>Female<br/>Fibroblasts--drug effects<br/>Humans<br/>JNK Mitogen-Activated Protein Kinases--metabolism<br/>MAP Kinase Signaling System--drug effects<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Mitochondria--drug effects<br/>Models, Biological<br/>Osteosarcoma--enzymology<br/>Pentacyclic Triterpenes<br/>Phagosomes--drug effects<br/>Reactive Oxygen Species--metabolism<br/>Triterpenes--pharmacology<br/>Xenograft Model Antitumor Assays