Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells. [electronic resource]
- British journal of cancer Feb 2015
- 714-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1532-1827
10.1038/bjc.2015.4 doi
Adenoma--genetics Cell Membrane--metabolism Colorectal Neoplasms--genetics Food Glucose--deficiency Glycosylation Humans Neoplastic Stem Cells--metabolism Protein Stability Protein Transport Receptors, G-Protein-Coupled--genetics Stress, Physiological--physiology Tumor Cells, Cultured Tumor Microenvironment