TY  - GEN
AU  - Vosper,Jonathan
AU  - Masuccio,Alessia
AU  - Kullmann,Michael
AU  - Ploner,Christian
AU  - Geley,Stephan
AU  - Hengst,Ludger
TI  - Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation
SN  - 1949-2553
PY  - 2015///1125
KW  - Alkyl and Aryl Transferases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Antigens, CD
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cadherins
KW  - genetics
KW  - Cdh1 Proteins
KW  - Cell Proliferation
KW  - drug effects
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - metabolism
KW  - Cyclin-Dependent Kinase Inhibitor p27
KW  - Down-Regulation
KW  - Genes, APC
KW  - HeLa Cells
KW  - Humans
KW  - Hydroxymethylglutaryl-CoA Reductase Inhibitors
KW  - Lovastatin
KW  - Mice
KW  - NIH 3T3 Cells
KW  - Neoplasms
KW  - drug therapy
KW  - Polyisoprenyl Phosphates
KW  - Proteasome Endopeptidase Complex
KW  - Proteolysis
KW  - S-Phase Kinase-Associated Proteins
KW  - Signal Transduction
KW  - Time Factors
KW  - Transfection
KW  - U937 Cells
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.18632/oncotarget.3068
ER  -