TY - GEN AU - Goldman,I D AU - Matherly,L H TI - Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates SN - 0893-2751 PY - 1988///0304 KW - Antineoplastic Combined Chemotherapy Protocols KW - Biological Transport KW - Drug Administration Schedule KW - Folic Acid Antagonists KW - pharmacology KW - Humans KW - Leucovorin KW - administration & dosage KW - Methotrexate KW - Neoplasms KW - drug therapy KW - Nucleosides KW - Polyglutamic Acid KW - metabolism KW - Tetrahydrofolate Dehydrogenase N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review ER -