TY - GEN AU - Ye,Qi AU - Yao,Guangmin AU - Zhang,Mengke AU - Guo,Guoli AU - Hu,Yufeng AU - Jiang,Jue AU - Cheng,Ling AU - Shi,Jianguo AU - Li,Hua AU - Zhang,Yonghui AU - Liu,Hudan TI - A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling SN - 1460-2180 PY - 2015///0624 KW - Animals KW - Antineoplastic Agents, Phytogenic KW - pharmacology KW - Apoptosis KW - drug effects KW - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors KW - metabolism KW - Cell Proliferation KW - Colorectal Neoplasms KW - drug therapy KW - Diterpenes, Kaurane KW - chemistry KW - Drug Screening Assays, Antitumor KW - Gene Expression Regulation, Neoplastic KW - HCT116 Cells KW - Humans KW - Mice, Inbred BALB C KW - Molecular Docking Simulation KW - Molecular Targeted Therapy KW - Transcription Factor 4 KW - Transcription Factors KW - Tumor Cells, Cultured KW - Wnt Signaling Pathway KW - Xenograft Model Antitumor Assays KW - beta Catenin KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/carcin/bgv003 ER -