Ye, Qi <br/><br/>
A novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling.  [electronic resource] 

 -  Carcinogenesis  Mar 2015 
 - 318-26 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1460-2180 
<br/><br/><label>Standard No.: </label>10.1093/carcin/bgv003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents, Phytogenic--pharmacology<br/>Apoptosis--drug effects<br/>Basic Helix-Loop-Helix Leucine Zipper Transcription Factors--metabolism<br/>Cell Proliferation--drug effects<br/>Colorectal Neoplasms--drug therapy<br/>Diterpenes, Kaurane--chemistry<br/>Drug Screening Assays, Antitumor<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>HCT116 Cells--drug effects<br/>Humans<br/>Mice, Inbred BALB C<br/>Molecular Docking Simulation<br/>Molecular Targeted Therapy<br/>Transcription Factor 4<br/>Transcription Factors--metabolism<br/>Tumor Cells, Cultured<br/>Wnt Signaling Pathway--drug effects<br/>Xenograft Model Antitumor Assays<br/>beta Catenin--antagonists & inhibitors