TY  - GEN
AU  - Filser,Severin
AU  - Ovsepian,Saak V
AU  - Masana,Mercè
AU  - Blazquez-Llorca,Lidia
AU  - Brandt Elvang,Anders
AU  - Volbracht,Christiane
AU  - Müller,Marianne B
AU  - Jung,Christian K E
AU  - Herms,Jochen
TI  - Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions
SN  - 1873-2402
PY  - 2016///0101
KW  - Amyloid Precursor Protein Secretases
KW  - deficiency
KW  - Amyloid beta-Peptides
KW  - metabolism
KW  - Animals
KW  - Aspartic Acid Endopeptidases
KW  - Brain
KW  - anatomy & histology
KW  - Cognition
KW  - physiology
KW  - Cognitive Dysfunction
KW  - chemically induced
KW  - Dendritic Spines
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - Exploratory Behavior
KW  - Humans
KW  - Maze Learning
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Peptide Fragments
KW  - Pyramidal Cells
KW  - Pyrimidines
KW  - Pyrimidinones
KW  - pharmacology
KW  - Synaptic Potentials
KW  - Thiazines
KW  - Thiophenes
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.biopsych.2014.10.013
ER  -