Jung, Kyong-Jin

Carnosic acid sensitized TRAIL-mediated apoptosis through down-regulation of c-FLIP and Bcl-2 expression at the post translational levels and CHOP-dependent up-regulation of DR5, Bim, and PUMA expression in human carcinoma caki cells. [electronic resource] - Oncotarget Jan 2015 - 1556-68 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1949-2553

10.18632/oncotarget.2727 doi


Abietanes--administration & dosage
Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis Regulatory Proteins--biosynthesis
Bcl-2-Like Protein 11
Breast Neoplasms--drug therapy
CASP8 and FADD-Like Apoptosis Regulating Protein--biosynthesis
Carcinoma, Hepatocellular--drug therapy
Carcinoma, Renal Cell--drug therapy
Cell Line, Tumor
Down-Regulation--drug effects
Drug Synergism
Female
Humans
Kidney Neoplasms--drug therapy
Liver Neoplasms--drug therapy
Membrane Proteins--biosynthesis
Mice
Neoplasms--drug therapy
Plant Extracts--administration & dosage
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-bcl-2--biosynthesis
Receptors, TNF-Related Apoptosis-Inducing Ligand--biosynthesis
TNF-Related Apoptosis-Inducing Ligand--administration & dosage
Transcription Factor CHOP--metabolism
Up-Regulation--drug effects