TY - GEN AU - Souza-Silva,Franklin AU - Bourguignon,Saulo Cabral AU - Pereira,Bernardo Acácio Santini AU - Côrtes,Luzia Monteiro de Castro AU - de Oliveira,Luiz Filipe Gonçalves AU - Henriques-Pons,Andrea AU - Finkelstein,Lea Cysne AU - Ferreira,Vitor Francisco AU - Carneiro,Paula Fernandes AU - de Pinho,Rosa Teixeira AU - Caffarena,Ernesto Raul AU - Alves,Carlos Roberto TI - Epoxy-α-lapachone has in vitro and in vivo anti-leishmania (Leishmania) amazonensis effects and inhibits serine proteinase activity in this parasite SN - 1098-6596 PY - 2015///1215 KW - Animals KW - Antipain KW - pharmacology KW - Antiprotozoal Agents KW - Computer Simulation KW - Leishmania mexicana KW - drug effects KW - Leishmaniasis, Cutaneous KW - drug therapy KW - Mice KW - Mice, Inbred BALB C KW - Naphthoquinones KW - Protein Binding KW - Serine Endopeptidases KW - metabolism KW - Serine Proteinase Inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/AAC.04742-14 ER -