Metformin and Rapamycin Reduce Pancreatic Cancer Growth in Obese Prediabetic Mice by Distinct MicroRNA-Regulated Mechanisms. [electronic resource]
- Diabetes May 2015
- 1632-42 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1939-327X
10.2337/db14-1132 doi
Animals Body Weight Cell Cycle--drug effects Diet, Diabetic Energy Intake Glucose Intolerance Hypoglycemic Agents--therapeutic use Immunosuppressive Agents--therapeutic use Male Metformin--therapeutic use Mice Mice, Inbred C57BL Mice, Obese MicroRNAs--genetics Neoplasms, Experimental--drug therapy Pancreatic Neoplasms--drug therapy Prediabetic State--drug therapy Random Allocation Sirolimus--therapeutic use Snail Family Transcription Factors Transcription Factors--genetics Vimentin--genetics