TY - GEN AU - Ishchenko,Alexey AU - Zhang,Lin AU - Le Brazidec,Jean-Yves AU - Fan,Junhua AU - Chong,Jer Hong AU - Hingway,Aparna AU - Raditsis,Annie AU - Singh,Latika AU - Elenbaas,Brian AU - Hong,Victor Sukbong AU - Marcotte,Doug AU - Silvian,Laura AU - Enyedy,Istvan AU - Chao,Jianhua TI - Structure-based design of low-nanomolar PIM kinase inhibitors SN - 1464-3405 PY - 2015///0915 KW - Binding Sites KW - Crystallography, X-Ray KW - Drug Design KW - Hydrogen Bonding KW - Molecular Dynamics Simulation KW - Protein Binding KW - Protein Isoforms KW - antagonists & inhibitors KW - Protein Kinase Inhibitors KW - chemical synthesis KW - Protein Structure, Tertiary KW - Proto-Oncogene Proteins c-pim-1 KW - Static Electricity KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2014.12.041 ER -