Isolation Housing Exacerbates Alzheimer's Disease-Like Pathophysiology in Aged APP/PS1 Mice. [electronic resource]
- The international journal of neuropsychopharmacology Jan 2015
- pyu116 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1469-5111
10.1093/ijnp/pyu116 doi
Aging--metabolism Alzheimer Disease--genetics Amyloid Precursor Protein Secretases--metabolism Amyloid beta-Protein Precursor--genetics Animals Atrophy--pathology Behavior, Animal Cognition Disease Models, Animal Hippocampus--metabolism Inflammation--pathology Locomotion Male Maze Learning Mice Mice, Transgenic Motor Activity Myelin Sheath--pathology Neprilysin--metabolism Neuroglia--pathology Plaque, Amyloid--pathology Social Isolation--psychology Synapses--pathology