TY - GEN AU - Griebel,Guy AU - Pichat,Philippe AU - Beeské,Sandra AU - Leroy,Thibaud AU - Redon,Nicolas AU - Jacquet,Agnès AU - Françon,Dominique AU - Bert,Lionel AU - Even,Luc AU - Lopez-Grancha,Mati AU - Tolstykh,Tatiana AU - Sun,Fangxian AU - Yu,Qunyan AU - Brittain,Scott AU - Arlt,Heike AU - He,Timothy AU - Zhang,Bailin AU - Wiederschain,Dmitri AU - Bertrand,Thomas AU - Houtmann,Jacques AU - Rak,Alexey AU - Vallée,François AU - Michot,Nadine AU - Augé,Franck AU - Menet,Véronique AU - Bergis,Olivier E AU - George,Pascal AU - Avenet,Patrick AU - Mikol,Vincent AU - Didier,Michel AU - Escoubet,Johanna TI - Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents SN - 2045-2322 PY - 2015///1103 KW - Acetylcholine KW - metabolism KW - Administration, Oral KW - Analgesics KW - chemistry KW - Animals KW - Arachidonic Acids KW - Binding Sites KW - Brain KW - Cannabinoid Receptor Antagonists KW - pharmacology KW - Carbamates KW - Chromatography, High Pressure Liquid KW - Crystallography, X-Ray KW - Disease Models, Animal KW - Electric Stimulation KW - Endocannabinoids KW - Enzyme Inhibitors KW - Glycerides KW - Hippocampus KW - drug effects KW - Humans KW - Hydrolysis KW - In Vitro Techniques KW - Learning KW - Long-Term Potentiation KW - Mass Spectrometry KW - Memory, Short-Term KW - Mice KW - Mice, Inbred C57BL KW - Mice, SCID KW - Monoacylglycerol Lipases KW - antagonists & inhibitors KW - Pain KW - drug therapy KW - Piperidines KW - Protein Structure, Tertiary KW - Pyrazoles KW - Rimonabant KW - Seizures KW - Sulfonamides N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/srep07642 ER -