Griebel, Guy <br/><br/>
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.  [electronic resource] 

 -  Scientific reports  Jan 2015 
 - 7642 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep07642  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholine--metabolism<br/>Administration, Oral<br/>Analgesics--chemistry<br/>Animals<br/>Arachidonic Acids--chemistry<br/>Binding Sites<br/>Brain--metabolism<br/>Cannabinoid Receptor Antagonists--pharmacology<br/>Carbamates--chemistry<br/>Chromatography, High Pressure Liquid<br/>Crystallography, X-Ray<br/>Disease Models, Animal<br/>Electric Stimulation<br/>Endocannabinoids--chemistry<br/>Enzyme Inhibitors--chemistry<br/>Glycerides--chemistry<br/>Hippocampus--drug effects<br/>Humans<br/>Hydrolysis<br/>In Vitro Techniques<br/>Learning--drug effects<br/>Long-Term Potentiation--drug effects<br/>Mass Spectrometry<br/>Memory, Short-Term--drug effects<br/>Mice<br/>Mice, Inbred C57BL<br/>Mice, SCID<br/>Monoacylglycerol Lipases--antagonists & inhibitors<br/>Pain--drug therapy<br/>Piperidines--pharmacology<br/>Protein Structure, Tertiary<br/>Pyrazoles--pharmacology<br/>Rimonabant<br/>Seizures--drug therapy<br/>Sulfonamides--chemistry