TY - GEN AU - Petrylak,Daniel P AU - Gandhi,Jitendra G AU - Clark,William R AU - Heath,Elisabeth AU - Lin,Jianqing AU - Oh,William K AU - Agus,David B AU - Carthon,Bradley AU - Moran,Susan AU - Kong,Ning AU - Suri,Ajit AU - Bargfrede,Michael AU - Liu,Glenn TI - Phase 1/2 study of orteronel (TAK-700), an investigational 17,20-lyase inhibitor, with docetaxel-prednisone in metastatic castration-resistant prostate cancer SN - 1573-0646 PY - 2016///0119 KW - Aged KW - Aged, 80 and over KW - Antineoplastic Agents KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - Dehydroepiandrosterone Sulfate KW - blood KW - Disease Progression KW - Disease-Free Survival KW - Docetaxel KW - Dose-Response Relationship, Drug KW - Humans KW - Imidazoles KW - Male KW - Middle Aged KW - Naphthalenes KW - Prednisone KW - Prostate-Specific Antigen KW - Prostatic Neoplasms, Castration-Resistant KW - drug therapy KW - Steroid 17-alpha-Hydroxylase KW - antagonists & inhibitors KW - Taxoids KW - Testosterone N1 - Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10637-014-0199-x ER -